Introducing Salmonella Vetovax™ SRP®
Salmonella Vetovax™ SRP® is a vaccine using the patented siderophore receptor and porin (SRP) technology, made from Salmonella Newport bacterial extract, that has been shown to be effective for vaccination of healthy cattle 6 months of age or older against infection caused by Salmonella Newport.
The Salmonella impact on profitability
Prevalent pathogen, especially in large herds, has extended survival in the environment1 and is a significant zoonotic pathogen: salmonellosis may result in food-borne exposure of humans to Salmonella through milk or meat products.2
Losses in feed efficiency, weight gain, milk production and increased cull rates are linked to subclinical Salmonella infections.3
Causes a number of diseases such as acute neonatal diarrhea, pneumonia, gastroenteritis in adult animals, and septicemia.
A cause of abortions in cows and heifers.
Protect the herd with Salmonella Vetovax™ SRP®
An innovative technology designed to address Salmonella Newport outbreaks and keep milk production flowing.
Limiting Salmonella infections is important to mitigate zoonotic risk and improve the health status and productivity of dairy herds. Clinical salmonellosis is urgently addressed, while subclinical infections commonly go unnoticed.4 Subclinical Salmonella infections make diagnosis difficult, as overt clinical signs are absent, and fecal shedding occurs intermittently. Productivity losses in the form of reduced milk yield and lagging reproductive performance are masked as infected animals often appear healthy.5
Source for the data provided here
1 NATIONAL ANIMAL HEALTH MONITORING SYSTEM. Salmonella and Campylobacter on U.S. dairy operations, 1996-2007. APHIS Info Sheet, July 2009, #N562.0709.
2 LONERAGAN, G.H., et al. Salmonella in Cull Dairy Cattle of the Texas High Plains. 89th Annual Meeting of the Conference of Research Workers in Animal Diseases, Dec. 7-9, 2008, Chicago, Ill.
4 FOSSLER, C.P., WELLS, S.J., KANEENE, J.B. et al.. (2004). Prevalence of Salmonella spp on conventional and organic dairy farms, J Am Vet Med Assoc. 225:567-573.
5 HERMESCH, D.R., THOMSON, D.U., LONERAGAN, G.H.,RENTER, D.R., WHITE, B.J. (Sept. 2008). Effects of a commercially available vaccine against Salmonella enterica serotype Newport on milk production, somatic cell count, and shedding of Salmonella organisms in female dairy cattle with no clinical signs of salmonellosis, AJVR, 69(9): 1229-1234.
Read the article
"In May 2020, a vaccine for the control of salmonellosis in cattle became available in Canada; it employs siderophore receptors and porins (SRP). Siderophore receptors are specialized channels for the transport of iron into the cell, a nutrient essential for the development and metabolism of most pathogenic bacteria. By stimulating an immune response against these receptors, iron and other nutrients essential to the bacteria are unable to effectively pass through their cell wall, causing their death. This technology relies on the fact that siderophore receptors are similar among salmonella serotypes, meaning the vaccine could help control infections of different salmonella serotypes."
Vaccination against salmonellosis: Another string to your bow
This article was developed by Dr Virginie Filteau, Technical Services Veterinarian for the Production Animals Business Unit at Vetoquinol